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Synonyms: hydrogen sulfide
Compound class:
Inorganic
Comment: H2S is derived from L-cysteine by the enzymes cystathionine β-synthase, cystathionine γ-lyase, and 3-mercaptopyruvate sulfurtransferase. Like NO, hydrogen sulfide is involved in the relaxation of smooth muscle that causes erection of the penis, presenting possible new therapy opportunities for erectile dysfunction.
Novel H2S-releasing drugs are being developed for anti-inflammatory activity and these are receiving additional attention for chemoprevention of cancers [1]. |
| References |
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1. Flannigan KL, Wallace JL. (2015)
Hydrogen sulfide-based anti-inflammatory and chemopreventive therapies: an experimental approach. Curr Pharm Des, 21 (21): 3012-22. [PMID:26004409] |
