Ligand id: 9601

Name: anlotinib

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 82.39
Molecular weight 407.16
XLogP 3.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Chen GP. (2008)
Spiro substituted compounds as angiogenesis inhibitors.
Patent number: WO2008112407 A1. Assignee: Advenchen Laboratories, Llc. Priority date: 14/03/2007. Publication date: 18/09/2008.
2. Chen GP, Yan C. (2016)
Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl) cyclopropanamine, its crystalline form and its salts.
Patent number: WO2016179123. Assignee: Advenchen Pharmaceuticals, LLC. Priority date: 04/05/2015. Publication date: 10/11/2016.