exendin-4   Click here for help

GtoPdb Ligand ID: 1135

Synonyms: AC 2993 | AC002993 | AC2993A | Bydureon® | Byetta®
Approved drug
exendin-4 is an approved drug (FDA (2005), EMA (2006))
Comment: This peptide is found in the venom of the Gila monster Heloderma suspectum. Exenatide is the synthetic form of the peptide used in clinical practice. Exendin-4 is a GLP-1 analogue/mimetic [1]. There is some ambiguity surrounding the exact stereochemistry of exendin-4. Representations of the peptide's full chemical structure can be accessed using the PubChem, ChEMBL and ChEBI links that we provide in the Database Links table.
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View more information in the IUPHAR Pharmacology Education Project: exenatide