exendin-4   Click here for help

GtoPdb Ligand ID: 1135

Synonyms: AC 2993 | AC002993 | AC2993A | Bydureon® | Byetta®
Approved drug
exendin-4 is an approved drug (FDA (2005), EMA (2006))
Comment: This peptide is found in the venom of the Gila monster Heloderma suspectum. Exenatide is the synthetic form of the peptide used in clinical practice. Exendin-4 is a GLP-1 analogue/mimetic [1]. There is some ambiguity surrounding the exact stereochemistry of exendin-4. Representations of the peptide's full chemical structure can be accessed using the PubChem, ChEMBL and ChEBI links that we provide in the Database Links table.
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Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (FDA (2005), EMA (2006))
International Nonproprietary Names Click here for help
INN number INN
8219 exenatide
Synonyms Click here for help
AC 2993 | AC002993 | AC2993A | Bydureon® | Byetta®
Database Links Click here for help
BindingDB Ligand 50241203
CAS Registry No. 141758-74-9 (source: Scifinder)
ChEMBL Ligand CHEMBL414357
DrugBank Ligand DB01276
GtoPdb PubChem SID 135652150
PubChem CID 16157882
Search PubMed clinical trials exenatide
Search PubMed titles exenatide
Search PubMed titles/abstracts exenatide
UniProtKB P26349 (Hsu)
Wikipedia Exenatide

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Cat. No. 1933