paracetamol   Click here for help

GtoPdb Ligand ID: 5239

Synonyms: acetaminophen | N-Acetyl-p-aminophenol | Panadol® | Tylenol®
Approved drug PDB Ligand
paracetamol is an approved drug (FDA (1968))
Compound class: Synthetic organic
Comment: Paracetamol is approved by the US FDA as acetaminophen. It is a widely used analgesic and antipyretic drug. Despite its widespread use the mechanism of action of paracetamol is incompletely understood [2].
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: paracetamol

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 49.33
Molecular weight 151.06
XLogP 0.87
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CC(=O)Nc1ccc(cc1)O
Isomeric SMILES CC(=O)Nc1ccc(cc1)O
InChI InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)