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Synonyms: RSLV132
Compound class:
Peptide
Comment: RSLV-132 is a fully human biologic fusion protein that is comprised of human RNase fused to the Fc domain of human IgG1 [1]. The peptide sequence of RSLV-132 has not yet been formally disclosed. It is designed to digest circulating extracellular RNA autoantigens that are known to trigger inflammatory responses in some chronic autoinflammatory conditions. RSLV-132 is proposed for anti-inflammatory and immunomodulatory activities in such conditions. It may also be effective in reducing viral RNA load and/or persistence in virus reservoirs.
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