Synonyms: CP-14,445 | CP-14445
oxantel is an approved drug
Compound class:
Synthetic organic
Comment: Oxantel is an anthelmintic agent. In addition, it inhibits fumarate reductase, an enzyme that is crucial for the survival of pathogenic bacteria in the biofilm in periodontal pockets. It has been suggested that oxantel might guard against chronic periodontitis, but efficacy of this potential antibacterial function is yet to be confirmed [1-2].
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes |
IUPAC Name |
3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol |
International Nonproprietary Names | |
INN number | INN |
3599 | oxantel |
Synonyms |
CP-14,445 | CP-14445 |
Database Links | |
Specialist databases | |
Antibiotic DB | Oxantel |
Other databases | |
CAS Registry No. | 36531-26-7 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL1240977 |
DrugBank Ligand | DB13670 |
DrugCentral Ligand | 4005 |
GtoPdb PubChem SID | 405560281 |
PubChem CID | 5281087 |
Search Google for chemical match using the InChIKey | VRYKTHBAWRESFI-VOTSOKGWSA-N |
Search Google for chemicals with the same backbone | VRYKTHBAWRESFI |
Search PubMed clinical trials | oxantel |
Search PubMed titles | oxantel |
Search PubMed titles/abstracts | oxantel |
UniChem Compound Search for chemical match using the InChIKey | VRYKTHBAWRESFI-VOTSOKGWSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | VRYKTHBAWRESFI-VOTSOKGWSA-N |