ofloxacin   Click here for help

GtoPdb Ligand ID: 10918

Synonyms: DL-8280 | Exocin® (eye drops) | Floxin® | HOE-280 | OFX | Tarivid®
Approved drug
ofloxacin is an approved drug (FDA (1990), UK (1992))
Compound class: Synthetic organic
Comment: Ofloxacin is a second generation fluoroquinolone antibacterial.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 75.01
Molecular weight 361.14
XLogP 3.7
No. Lipinski's rules broken 0
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Canonical SMILES CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C
Isomeric SMILES CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C
InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1990), UK (1992))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
International Nonproprietary Names Click here for help
INN number INN
5322 ofloxacin
Synonyms Click here for help
DL-8280 | Exocin® (eye drops) | Floxin® | HOE-280 | OFX | Tarivid®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Ofloxacin
GPCRdb Ligand ofloxacin
Other databases
CAS Registry No. 82419-36-1 (source: PubChem)
DrugBank Ligand DB01165
DrugCentral Ligand 1981
GtoPdb PubChem SID 405560359
PubChem CID 4583
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UniChem Compound Search for chemical match using the InChIKey GSDSWSVVBLHKDQ-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey GSDSWSVVBLHKDQ-UHFFFAOYSA-N