abrilumab   Click here for help

GtoPdb Ligand ID: 11531

Synonyms: AMG 181 | AMG-181 | MEDI-7183 | MEDI7183
Immunopharmacology Ligand
Compound class: Antibody
Comment: Abrilumab (AMG-181, MEDI-7183) is a fully human IgG2κ monoclonal antibody which selectively targets α4β7 integrin heterodimers [1] that was developed by MedImmune. It was designed for the treatment of inflammatory bowel diseases (ulcerative colitis [2], and Crohn's disease).
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9921 abrilumab
Synonyms Click here for help
AMG 181 | AMG-181 | MEDI-7183 | MEDI7183
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 495
Other databases
DrugBank Ligand DB15076
GtoPdb PubChem SID 441604903
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