perphenazine   Click here for help

GtoPdb Ligand ID: 209

Synonyms: Decentan® | Fentazin® | Trilafon®
Approved drug
perphenazine is an approved drug (FDA (1957))
Compound class: Synthetic organic
Comment: Perphenazine is a typical antipsychotic drug, acting principally as a dopamine D2 receptor antagonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 55.25
Molecular weight 403.15
XLogP 3.86
No. Lipinski's rules broken 0
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Canonical SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
Isomeric SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
InChI InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
637 perphenazine
Synonyms Click here for help
Decentan® | Fentazin® | Trilafon®
Database Links Click here for help
Specialist databases
GPCRdb Ligand perphenazine
Other databases
BindingDB Ligand 50130273
CAS Registry No. 58-39-9
DrugBank Ligand DB00850
DrugCentral Ligand 2113
GtoPdb PubChem SID 135650810
PubChem CID 4748
Search Google for chemical match using the InChIKey RGCVKNLCSQQDEP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RGCVKNLCSQQDEP
Search PubMed clinical trials perphenazine
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UniChem Compound Search for chemical match using the InChIKey RGCVKNLCSQQDEP-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey RGCVKNLCSQQDEP-UHFFFAOYSA-N
Wikipedia Perphenazine