IFN-α2   Click here for help

GtoPdb Ligand ID: 4960

Synonyms: IFN-alpha-2 | interferon alpha-2 | Roferon A®
Approved drug Immunopharmacology Ligand
IFN-α2 is an approved drug (FDA (1989))
Comment: IFN-α2 is a type I IFN. The sequence of the recombinant peptide used clinically and known as interferon alfa-2a, is identical to that of human IFN-α2. Interferon α-2a has anti-viral, immunomodulatory and antineoplastic actions.
Pegylated IFN-α-2a is on the World Health Organization's List of Essential Medicines.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interferons
Approved drug? Yes (FDA (1989))
Synonyms Click here for help
IFN-alpha-2 | interferon alpha-2 | Roferon A®
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IFNA2 interferon alpha 2 Human prepro-interferon alpha-2 alpha-2a interferon, IFNA, IFN-alphaA, interferon, alpha 2, interferon alpha 2b, interferon alpha A
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 624
Other databases
Ensembl Gene ENSG00000188379 (Hs)
GtoPdb PubChem SID 178101658
Human Protein Atlas ENSG00000188379 (Hs)
UniProtKB P01563 (Hs)
Wikipedia IFNA2