enalapril

Ligand id: 6322

Name: enalapril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 95.94
Molecular weight 376.2
XLogP 2.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1985))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
Is prodrug? Yes
Active form enalaprilat
IUPAC Name
(2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid
International Nonproprietary Names
INN number INN
5117 enalapril
Synonyms
Enaladex® | Vasotec®
Comments
Pro-drug for elanoprilat
Database Links
CAS Registry No. 75847-73-3 (source: PubChem)
ChEBI CHEBI:4784
ChEMBL Ligand CHEMBL578
DrugBank Ligand DB00584
GtoPdb PubChem SID 178102940
PubChem CID 5388962
Search Google for chemical match using the InChIKey GBXSMTUPTTWBMN-XIRDDKMYSA-N
Search Google for chemicals with the same backbone GBXSMTUPTTWBMN
Search PubMed clinical trials enalapril
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Search UniChem for chemical match using the InChIKey GBXSMTUPTTWBMN-XIRDDKMYSA-N
Search UniChem for chemicals with the same backbone GBXSMTUPTTWBMN
Wikipedia Enalapril