ropinirole   Click here for help

GtoPdb Ligand ID: 7295

Synonyms: Requip® | SK&F-101468-A | SK&F-101468A
Approved drug
ropinirole is an approved drug (FDA (1997), EMA (2006))
Compound class: Synthetic organic
Comment: Ropinirole is a dopamine agonist. This drug is active at the dopamine-D2 and -D3 receptor subtypes, both centrally and peripherally.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 35.83
Molecular weight 260.19
XLogP 2.56
No. Lipinski's rules broken 0
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Canonical SMILES CCCN(CCC)CCc1cccc2c1CC(=N2)O
Isomeric SMILES CCCN(CCC)CCc1cccc2c1CC(=N2)O
InChI InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1997), EMA (2006))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6436 ropinirole
Synonyms Click here for help
Requip® | SK&F-101468-A | SK&F-101468A
Database Links Click here for help
Specialist databases
GPCRdb Ligand ropinirole
Other databases
CAS Registry No. 91374-21-9
DrugBank Ligand DB00268
DrugCentral Ligand 2402
GtoPdb PubChem SID 178103868
PubChem CID 5095
Search Google for chemical match using the InChIKey UHSKFQJFRQCDBE-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey UHSKFQJFRQCDBE-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey UHSKFQJFRQCDBE-UHFFFAOYSA-N
Wikipedia Ropinirole