epratuzumab   Click here for help

GtoPdb Ligand ID: 8088

Synonyms: 90Y-DOTA-hLL2 | 90Y-epratuzumab tetraxetan | 90Y-hLL2 | AMG-412 | IMMU-hLL2 | LymphoCide® (proposed proprietary name)
Immunopharmacology Ligand
Compound class: Antibody
Comment: Epratuzumab is a humanized monoclonal antibody. It is derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). Epratuzumab has antineoplastic and antiinflammatory actions [1].
The antibody can be conjugated with tetraxetan (DOTA) which allows chelation of radionucleotides such as yttrium-90 [5].
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
7920 epratuzumab
Synonyms Click here for help
90Y-DOTA-hLL2 | 90Y-epratuzumab tetraxetan | 90Y-hLL2 | AMG-412 | IMMU-hLL2 | LymphoCide® (proposed proprietary name)
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 40
Other databases
DrugBank Ligand DB04958
GtoPdb PubChem SID 249565768
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Wikipedia Epratuzumab