Synonyms: BMS-936557 | MDX-1100
Compound class:
Antibody
Comment: Eldelumab (BMS-936557 and formerly MDX-1100) is a a fully human monoclonal antibody targeting the chemokine CXCL10 (a.k.a. interferon-γ-inducible protein-10 or IP-10) [1]. It is being investigated for its anti-inflammatory action in autoimmune conditions.
BLAST peptide sequence analysis reveals exact matches with heavy and light chain variable regions claimed in patent US8258266, and identify eldelumab as clone 6A5 [1]. |
Classification | |
Compound class | Antibody |
International Nonproprietary Names | |
INN number | INN |
9746 | eldelumab |
Synonyms |
BMS-936557 | MDX-1100 |
Database Links | |
Specialist databases | |
IMGT/mAb-DB | 463 |
Other databases | |
GtoPdb PubChem SID | 315661132 |
Search PubMed clinical trials | eldelumab |
Search PubMed titles | eldelumab |
Search PubMed titles/abstracts | eldelumab |