dacarbazine

Ligand id: 9075

Name: dacarbazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 95.44
Molecular weight 182.09
XLogP -1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1975))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
International Nonproprietary Names
INN number INN
3232 dacarbazine
Synonyms
DTIC-Dome®
Comments
Dacarbazine is a triazine DNA alkylating agent.
Database Links
CAS Registry No. 4342-03-4 (source: WHO INN record)
ChEMBL Ligand CHEMBL476
DrugBank Ligand DB00851
GtoPdb PubChem SID 315661160
PubChem CID 5353562
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