GSK2981278

Ligand id: 9661

Name: GSK2981278

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 84.45
Molecular weight 461.22
XLogP 4.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-(oxan-4-ylmethoxy)benzenesulfonamide
Comments
GSK2981278 is a potent and selective inverse agonist of the nuclear receptor retinoid-related orphan receptor, RORγ [2]. It has been investigated for anti-inflammatory potential.
Database Links
CAS Registry No. 1474110-21-8 (source: PubChem)
GtoPdb PubChem SID 348353620
PubChem CID 89875987
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Search UniChem for chemicals with the same backbone LZLBRISQTJVZNP