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target has curated data in GtoImmuPdb
Target id: 1714
Nomenclature: Oncostatin M-specific receptor, β subunit
Family: IL-6 receptor family
| Quaternary Structure: Complexes |
| Interleukin-31 receptor |
| Oncostatin-M receptor |
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 979 | 5p13.1 | OSMR | oncostatin M receptor | |
| Mouse | 1 | 971 | 15 3.3 cM | Osmr | oncostatin M receptor | |
| Rat | 1 | 962 | 2q16 | Osmr | oncostatin M receptor | |
| Previous and Unofficial Names |
| IL-31 receptor subunit beta | IL-31RB | interleukin-31 receptor subunit beta | oncostatin M receptor | OSMRB |
| Database Links |
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| Alphafold | Q99650 (Hs), O70458 (Mm), Q65Z14 (Rn) |
| CATH/Gene3D | 2.60.40.10 |
| ChEMBL Target | CHEMBL4630885 (Hs) |
| Ensembl Gene | ENSG00000145623 (Hs), ENSMUSG00000022146 (Mm), ENSRNOG00000033192 (Rn) |
| Entrez Gene | 9180 (Hs), 18414 (Mm), 310132 (Rn) |
| Human Protein Atlas | ENSG00000145623 (Hs) |
| KEGG Gene | hsa:9180 (Hs), mmu:18414 (Mm), rno:310132 (Rn) |
| OMIM | 601743 (Hs) |
| Pharos | Q99650 (Hs) |
| UniProtKB | Q99650 (Hs), O70458 (Mm), Q65Z14 (Rn) |
| Wikipedia | OSMR (Hs) |
| Immunopharmacology Comments |
| Oncostatin M-specific receptor, β subunit (OSMR) is a component of two functional heterodimeric receptor complexes: 1. OSMR+ interleukin-6 receptor, β subunit (IL6ST) forms the receptor for oncostatin M 2. OSMR+ interleukin-31 receptor, α subunit forms the receptor for IL-31 |
| Immuno Process Associations | ||
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IL-6 receptor family: Oncostatin M-specific receptor, β subunit. Last modified on 07/04/2017. Accessed on 09/09/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1714.
