Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	80	6q21	CD24	CD24 molecule
Mouse	-	76	10 B2; 10 23.01 cM	Cd24a	CD24a antigen
Rat	-	76	20q13	Cd24	CD24 molecule

Database Links
Ensembl Gene	ENSG00000272398 (Hs), ENSMUSG00000047139 (Mm), ENSRNOG00000000321 (Rn)
Entrez Gene	100133941 (Hs), 12484 (Mm), 25145 (Rn)
Human Protein Atlas	ENSG00000272398 (Hs)
KEGG Gene	hsa:100133941 (Hs), mmu:12484 (Mm), rno:25145 (Rn)
OMIM	600074 (Hs)
Pharos	P25063 (Hs)
RefSeq Nucleotide	NM_001291738 (Hs), NM_009846 (Mm), NM_012752 (Rn)
RefSeq Protein	NP_001278667 (Hs), NP_033976 (Mm), NP_036884 (Rn)
UniProtKB	P25063 (Hs), P24807 (Mm), Q07490 (Rn)
Wikipedia	CD24 (Hs)

Immunopharmacology Comments

CD24 is a small GPI-anchored sialoglycoprotein that is expressed by immune cells. It is involved in B cell and T cell functions. CD24 binds to SIGLEC10 in an interaction that selectively suppresses the immune response to danger-associated molecular patterns (DAMPs). This latter action is being exploited as a mechanism to reduce DAMP-induced inflammation in patients with COVID-19 and GvHD, using the CD24 mimetic MK-7110.

Cell Type Associations

Immuno Cell Type:  B cells Cell Ontology Term:   B cell (CL:0000236)

Immuno Cell Type:  T cells