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CD24 molecule

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 3170

Nomenclature: CD24 molecule

Family: CD molecules

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 80 6q21 CD24 CD24 molecule
Mouse - 76 10 B2; 10 23.01 cM Cd24a CD24a antigen
Rat - 76 20q13 Cd24 CD24 molecule
Database Links Click here for help
Ensembl Gene
Entrez Gene
Human Protein Atlas
RefSeq Nucleotide
RefSeq Protein
Immunopharmacology Comments
CD24 is a small GPI-anchored sialoglycoprotein that is expressed by immune cells. It is involved in B cell and T cell functions. CD24 binds to SIGLEC10 in an interaction that selectively suppresses the immune response to danger-associated molecular patterns (DAMPs). This latter action is being exploited as a mechanism to reduce DAMP-induced inflammation in patients with COVID-19 and GvHD, using the CD24 mimetic MK-7110.
Cell Type Associations
Immuno Cell Type:  B cells
Cell Ontology Term:   B cell (CL:0000236)
Immuno Cell Type:  T cells

How to cite this page

CD molecules: CD24 molecule. Last modified on 28/01/2021. Accessed on 20/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,