Synonyms: (-)-5'-CBD-DMH | (-)-5'-DMH-CBD | 1"',1'"-Dimethylheptylcannabidiol | 5-(1,1-Dimethylheptyl)cannabidiol | DMH-CBD
Compound class:
Synthetic organic
Comment: Cannabidiol-dimethylheptyl (-)-CBD-DMH ((-)-5'-CBD-DMH) is a synthetic homologue of cannabidiol. Structurally the pentyl chain of cannabidiol has been replaced by a dimethylheptyl chain, and it retains the same stereochemistry as natural cannabidiol. Like cannabidiol (-)-5'-DMH-CBD is not psychotropic, has anticonvulsant activity, and is not a CB1 receptor agonist [2].
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Bioactivity Comments |
(-)‐5′‐DMH‐CBD inhibits [14C]-anandamide uptake by RBL‐2H3 (rat basophilic leukemia) cells with an IC50 of 14 μM, but does not affect anandamide hydrolysis (so is not a FAAH inhibitor) [1]. |