fMet-Leu-Phe   Click here for help

GtoPdb Ligand ID: 1022

Abbreviated name: fMLP
Synonyms: fMetLeuPhe | formyl-Met-Leu-Phe
Comment: From the bacterium E.coli
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2D Structure
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Canonical SMILES CSCCC(C(=O)NC(C(=O)NC(C(=O)O)Cc1ccccc1)CC(C)C)NC=O
Isomeric SMILES CSCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)CC(C)C)NC=O
InChI InChI=1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Peptide transporter 1 1-2,10-11,17
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FPR2/ALX Hs Agonist Full agonist 6.4 pKd - 12
pKd 6.4 [12]
FPR1 Hs Agonist Full agonist 10.1 – 10.2 pEC50 - 6,13
pEC50 10.1 – 10.2 [6,13]
FPR1 Mm Agonist Full agonist 4.7 pEC50 - 8,14
pEC50 4.7 [8,14]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields