[125I]CGP 64213

Ligand id: 1076

Name: [125I]CGP 64213    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Topological polar surface area 166
Molecular weight 646.13
XLogP 3.34
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
GABAB receptor Rn Antagonist Antagonist 9.0 pKd - 1
pKd 9.0 (Kd 1x10-9 M) [1]
GABAB1 Rn Antagonist Antagonist 8.9 pKd - 2
pKd 8.9 [2]