[125I]CGP 64213

Ligand id: 1076

Name: [125I]CGP 64213    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Topological polar surface area 166
Molecular weight 646.13
XLogP 3.34
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Galvez T, Urwyler S, Pr├ęzeau L, Mosbacher J, Joly C, Malitschek B, Heid J, Brabet I, Froestl W, Bettler B et al.. (2000)
Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit.
Mol. Pharmacol., 57 (3): 419-26. [PMID:10692480]
2. Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W et al.. (1997)
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.
Nature, 386 (6622): 239-46. [PMID:9069281]