Synonyms: PPI-0903 | TAK-599 | Teflaro® | Zinforo®
ceftaroline fosamil is an approved drug (FDA (2010), EMA (2012))
Compound class:
Synthetic organic
Comment: Ceftaroline fosamil is a fifth-generation cephalosporin prodrug which is hydrolysed to the active form, ceftaroline, in vivo. It has anti-MRSA activity [1]. Ceftaroline was removed from the World Health Organization's List of Essential Medicines in 2019.
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Bioactivity Comments |
MIC90 for antibacterial activity against erythromycin-susceptible Streptococcus pyogenes and Streptococcus pneumoniae serotype 3 is ≤8 ng/ml in vitro [2-3]. |