Abbreviated name: DRV
Synonyms: Prezista® | TMC114 | UIC-94017
darunavir is an approved drug (FDA (2006), EMA (2007))
Compound class:
Synthetic organic
Comment: Darunavir is a second-generation human immunodeficiency virus 1 (HIV-1) protease inhibitor (PI) [2].
![]() View more information in the IUPHAR Pharmacology Education Project: darunavir |
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Bioactivity Comments |
Darunavir has potent in vitro activity against laboratory HIV-1 strains (an IC50 value of 0.003 μM for HIV-1LAI) and against multi-PI-resistant clinical isolates [2]. |