avdoralimab   Click here for help

GtoPdb Ligand ID: 11345

Synonyms: anti-hC5aR-32F3A6 GL | IPH-5401 | NN-8210 | NNC-0215-0384
Immunopharmacology Ligand
Compound class: Antibody
Comment: Avdoralimab (IPH5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1, and blocks C5a/C5aR1 signalling in subsets of myeloid-derived suppressor cells (MDSCs) and neutrophils. It has immunomodulating activity.
Targets where the ligand is described in the comment field
Target Comment