(2R,3R)-APDC

Ligand id: 1392

Name: (2R,3R)-APDC

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 112.65
Molecular weight 174.06
XLogP -3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
mGlu3 receptor Hs Agonist Full agonist 5.3 pKi - 1
pKi 5.3 [1]
mGlu2 receptor Hs Agonist Full agonist 5.0 pKi - 1
pKi 5.0 [1]
Ligand mentioned in the following text fields