Ligand id: 1392

Name: (2R,3R)-APDC

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 112.65
Molecular weight 174.06
XLogP -3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
mGlu3 receptor Hs Agonist Full agonist 5.3 pKi - 1
pKi 5.3 [1]
mGlu2 receptor Hs Agonist Full agonist 5.0 pKi - 1
pKi 5.0 [1]
Ligand mentioned in the following text fields