[Ala11, D-Leu15]orexin-B   

GtoPdb Ligand ID: 1700

Comment: Synthetic analogue of human orexin-B
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
OX2 receptor Hs Agonist Full agonist 7.6 – 9.9 pEC50 - 1-2
pEC50 7.6 – 9.9 [1-2]
OX1 receptor Hs Agonist Full agonist 6.1 – 7.3 pEC50 - 1-2
pEC50 6.1 – 7.3 [1-2]
Ligand mentioned in the following text fields