ADPβS

Ligand id: 1755

Name: ADPβS

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 6
Rotatable bonds 6
Topological polar surface area 267.24
Molecular weight 443.01
XLogP -2.35
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
P2Y1 receptor Hs Agonist Agonist 7.3 pEC50 - 3
pEC50 7.3 (EC50 4.99x10-8 M) [3]
P2Y11 receptor Hs Agonist Full agonist 3.8 – 4.5 pEC50 - 1
pEC50 3.8 – 4.5 [1]
P2Y12 receptor Hs Agonist Full agonist 8.6 pIC50 - 3
pIC50 8.6 [3]
P2Y13 receptor Hs Agonist Full agonist 5.7 pIC50 - 2
pIC50 5.7 [2]