dizocilpine

Ligand id: 2403

Name: dizocilpine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 12.03
Molecular weight 221.12
XLogP 3.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Kir3.2 Mm Gating inhibitor Antagonist 3.7 pIC50 - 1
pIC50 3.7 [1]
Voltage: -100.0 mV
GluN2A Hs Channel blocker - - - -
GluN2B Hs Channel blocker - - - -
GluN2C Hs Channel blocker - - - -
GluN2D Hs Channel blocker - - - -