Ligand id: 2633

Name: NH-3

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 109.9
Molecular weight 473.18
XLogP 7.44
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at nuclear hormone receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Thyroid hormone receptor-α Hs Antagonist Antagonist 7.6 pKd - 1
pKd 7.6 [1]
Thyroid hormone receptor-β Hs Antagonist Antagonist 7.0 pKd - 1
pKd 7.0 [1]
Ligand mentioned in the following text fields