NH-3

Ligand id: 2633

Name: NH-3

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 109.9
Molecular weight 473.18
XLogP 7.44
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Thyroid hormone receptor-α Hs Antagonist Antagonist 7.6 pKd - 1
pKd 7.6 [1]
Thyroid hormone receptor-β Hs Antagonist Antagonist 7.0 pKd - 1
pKd 7.0 [1]
Ligand mentioned in the following text fields