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Abbreviated name: QNB
Synonyms: Buzz | BZ | EA-2277 | Substance 78
Compound class: Synthetic organic
Comment: Quinuclidinyl benzilate is a anticholinergic glycolate that acts as a competitive, non-selective antagonist of muscarinic receptors in cardiac muscle, smooth muscle, exocrine glands and at postsynaptic receptors in neurons. It is a non-lethal incapacitating chemical warfare agent controlled under schedule 2 of the Chemical Weapons Convention of 1997.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|[3H]QNB binds to bovine brain preparations with a Kd of 0.24nM . Physostigmine is a specific antidote for quinuclidinyl benzilate poisoning.
|Selectivity at GPCRs
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