GR79236

Ligand id: 3288

Name: GR79236

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 145.78
Molecular weight 351.15
XLogP -0.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
A1 receptor Rn Agonist Agonist 8.5 pKi - 1
pKi 8.5 (Ki 3.1x10-9 M) [1]
A2A receptor Hs Agonist Agonist 5.9 pKi - 1
pKi 5.9 (Ki 1.3x10-6 M) [1]