RX821002

Ligand id: 526

Name: RX821002

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 52.08
Molecular weight 234.1
XLogP 0.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
α2A-adrenoceptor Hs Antagonist Antagonist 9.2 pKi - 1
pKi 9.2 [1]
α2C-adrenoceptor Hs Antagonist Antagonist 8.7 pKi - 1
pKi 8.7 [1]
α2B-adrenoceptor Hs Antagonist Antagonist 8.4 pKi - 1
pKi 8.4 [1]