amylin   

GtoPdb Ligand ID: 687

Abbreviated name: AMY
Species: Human
Natural/Endogenous Targets
Target
AMY1 receptor
AMY2 receptor
AMY3 receptor
CT receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
AMY1 receptor Hs Agonist Full agonist 9.0 – 9.7 pEC50 - 1
pEC50 9.0 – 9.7 (EC50 1x10-9 – 1.94x10-10 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
AMY3 receptor Hs Agonist Full agonist 8.9 – 9.6 pEC50 - 1
pEC50 8.9 – 9.6 (EC50 1.258x10-9 – 2.51x10-10 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
AMY2 receptor Hs Agonist Full agonist 8.3 – 9.1 pEC50 - 1
pEC50 8.3 – 9.1 (EC50 5.37x10-9 – 7.76x10-10 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
CT receptor Hs Agonist Full agonist 8.0 – 9.2 pEC50 - 1-3
pEC50 8.0 – 9.2 [1-3]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields