metreleptin   Click here for help

GtoPdb Ligand ID: 7333

Synonyms: Myalept® | r-metHuLeptin | R-methuleptin
Approved drug
metreleptin is an approved drug (FDA (2014), EMA (2018))
Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).
Bioactivity Comments
We have been unable to find publicly available affinity data for this drug at its proposed molecular target to substantiate its MMOA, and have therefore not tagged a primary drug target.