metreleptin   Click here for help

GtoPdb Ligand ID: 7333

Synonyms: Myalept® | r-metHuLeptin | R-methuleptin
Approved drug
metreleptin is an approved drug (FDA (2014), EMA (2018))
Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).
1. Unger, Rodger. (2010)
Methods for treating type I diabetes with leptin and leptin agonist.
Patent number: WO2010022262. Assignee: University Of Texas. Priority date: 20/08/2008. Publication date: 03/06/2010.