Synonyms: Myalept® | r-metHuLeptin | R-methuleptin
metreleptin is an approved drug (FDA (2014), EMA (2018))
Compound class:
Peptide
Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).
|
Chemical Modification | |
Cysteines 97 and 147 form a disulphide bridge. The peptide is not glycosylated. |