olodaterol   Click here for help

GtoPdb Ligand ID: 7543

Synonyms: BI-1744 | BI-1744-CL | Striverdi®
Approved drug Immunopharmacology Ligand
olodaterol is an approved drug (FDA (2014))
Compound class: Synthetic organic
Comment: Marketed formulations may contain olodaterol hydrochloride (PubChem CID 11711522).
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: olodaterol

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 100.05
Molecular weight 386.18
XLogP 1.81
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES COc1ccc(cc1)CC(NCC(c1cc(O)cc2c1OCC(=O)N2)O)(C)C
Isomeric SMILES COc1ccc(cc1)CC(NC[C@@H](c1cc(O)cc2c1OCC(=O)N2)O)(C)C
InChI InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1
InChI Key COUYJEVMBVSIHV-SFHVURJKSA-N
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
β2-adrenoceptor Primary target of this compound Hs Agonist Agonist 10.0 pIC50 - 1
pIC50 10.0 (IC50 1x10-10 M) [1]