WAY-100635

Ligand id: 80

Name: WAY-100635

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 48.91
Molecular weight 422.27
XLogP 4.51
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT1A receptor Hs Antagonist Antagonist 7.9 – 9.2 pKi - 2-3
pKi 7.9 – 9.2 (Ki 1.26x10-8 – 6.31x10-10 M) [2-3]
D4 receptor Hs Agonist Full agonist 7.8 pKi - 1
pKi 7.8 (Ki 1.6x10-8 M) [1]