L-740093

Ligand id: 881

Name: L-740093

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 77.04
Molecular weight 445.25
XLogP 4.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCK1 receptor Rn Antagonist Antagonist 5.8 pKi - 2
pKi 5.8 [2]
CCK2 receptor Hs Antagonist Antagonist 9.2 pIC50 - 1
pIC50 9.2 (IC50 6.3x10-10 M) [1]