Ligand id: 8879

Name: RBM2-1B

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 23
Topological polar surface area 74.63
Molecular weight 427.35
XLogP 10.05
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
delta 4-desaturase, sphingolipid 1 Hs Inhibitor Inhibition 4.7 pIC50 - 1
pIC50 4.7 (IC50 1.81x10-5 M) [1]
Description: Measured in a A549 cellular assay as the formation of CerC6NBD from dihydro CerC6NBD.