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Abbreviated name: CTGF
Compound class:
Endogenous peptide in human, mouse or rat
Comment: CTGF is a multifunctional growth factor secreted by vascular endothelial cells. CTGF is involved in cell migration, proliferation, and differentiation, plays a role chondrogenesis and is involved in the modulation of extracellular matrix deposition and angiogenesis [1-4]. CTGF is expressed at high levels in several types of human malignancies.
CTGF is a clinical molecular target for the identification of therapeutics for the treatment of fibroproliferative diseases. The signal peptide sequence is MTAASMGPVRVAFVVLLALCSRPAVG (1-26 of the full length amino acid sequence detailed here).
Species: Human
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| Other ligands which bind to or alter the activity of this ligand | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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