BI-6901

Ligand id: 9714

Name: BI-6901

Abbreviated name: BI 6901

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 119.37
Molecular weight 453.18
XLogP 2.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The racemate of BI-6901 (PubChem CID 44252324) exhibits in vitro and in vivo activity in various assays [1].
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR10 Hs Antagonist Antagonist 9.0 pIC50 - 1
pIC50 9.0 (IC50 1x10-9 M) [1]
CCR10 Mm Antagonist Antagonist 7.6 pIC50 - 1
pIC50 7.6 (IC50 2.5x10-8 M) [1]