Synonyms: ATV-006 | ATV006 | compound 5c [PMID: 34450570] | GS-5245 | GS5245
Compound class:
Synthetic organic
Comment: Obeldesivir (GS-5245) is an investigational nucleoside antiviral compound [1]. It is an ester prodrug of the predominant remdesivir metabolite GS-441524. As an inhibitor of viral RNA-dependent RNA polymerase (RdRP) it is likely to have activity against a range of filoviruses, paramyxoviruses, and coronaviruses, including SARS-CoV-2.
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No information available. |
Summary of Clinical Use |
GS-5245 is in clinical development as a COVID-19 therapeutic. |
Clinical Trials | |||||
Clinical Trial ID | Title | Type | Source | Comment | References |
NCT05996744 | Study of Obeldesivir in Children and Adolescents With COVID-19 | Phase 2/Phase 3 Interventional | Gilead Sciences | ||
NCT05603143 | Study of Obeldesivir in Participants With COVID-19 Who Have a High Risk of Developing Serious or Severe Illness | Phase 3 Interventional | Gilead Sciences | ||
NCT05715528 | Study of Obeldesivir in Nonhospitalized Participants With COVID-19 | Phase 3 Interventional | Gilead Sciences |