KW-2449

Ligand id: 5691

Name: KW-2449

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 61.02
Molecular weight 332.16
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Two early Phase I clinical trials (NCT00346632 and NCT00779480) of this compound in leukemias were terminated and development has ceased.