monomethyl fumarate

Ligand id: 5786

Name: monomethyl fumarate

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 63.6
Molecular weight 130.03
XLogP -0.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
MMF is an inhibitor of the KEAP1-Nrf2 protein-protein interaction, or functional Nrf2 activator. Compounds exhibiting this mechanism of action have anti-inflammatory and cytoprotective activity.