brazikumab   Click here for help

GtoPdb Ligand ID: 9293

Synonyms: AMG 139 | AMG-139 | MEDI2070
Immunopharmacology Ligand
Compound class: Antibody
Comment: Brazikumab (AMG 139, MEDI2070) is a fully human anti-IL23A monoclonal antibody in clinical development for autoimmune indications.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. BLAST peptide anaylsis reveals identical matches with peptides claimed in patent WO2011056600 [3].
Immunopharmacology Disease
Disease X-Refs Comment References
Psoriasis Disease Ontology: DOID:8893
 No progress beyond Phase 1 trial.
Crohn's disease Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206
 Phase 2 clinical candidate for CD (see NCT02574637).