compound 7d [PMID: 29672049]

Ligand id: 9937

Name: compound 7d [PMID: 29672049]

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 106.15
Molecular weight 490.32
XLogP 3.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Compound 7d is included in GtoImmuPdb as it has experimental anti-proliferative and pro-apoptotic effects on AML cells [1]. These effects are evident both in vitro and in vivo.