Compound class:
Synthetic organic
Comment: Benapenem is a carbapenem (β-lactam) with broad-spectrum antibacterial activity [2]. It has advanced to clinical evaluation as an intravenous treatment for urinary tract infections.
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References |
1. Ji XW, Xue F, Kang ZS, Zhong W, Kuan IH, Yang XP, Zhu X, Li Y, Lv Y. (2020)
Model-Informed Drug Development, Pharmacokinetic/Pharmacodynamic Cutoff Value Determination, and Antibacterial Efficacy of Benapenem against Enterobacteriaceae. Antimicrob Agents Chemother, 64 (3). [PMID:31844001] |
2. Zhao CY, Lv Y, Zhu Y, Wei MJ, Liu MY, Ji XW, Kang ZS, Xia YH, Tian JH, Ma Y et al.. (2019)
A First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese Volunteers. Antimicrob Agents Chemother, 63 (3). [PMID:30617093] |